The Rex Laboratory
Tonia S. Rex, Ph.D.
Vanderbilt Eye Institute
Department of Ophthalmology
& Visual Sciences
About the Lab
The Rex laboratory studies mechanisms underlying vision loss in ocular trauma and glaucoma tests the efficacy of neuroprotective therapies. Vision preserving therapies are needed for complex neurodegenerations in which there is no clear genetic cause, such as glaucoma and ocular trauma.
We identified a novel mutation in erythropoietin (EPO) that retains EPO’s neuroprotective
activity while attenuating production of red blood cells. This EPO (EPO-
In addition, we have generated and characterized a model of ocular trauma induced
by an over-